IFITM3 Peptide

Cat no: BS5762P

Supplier: Bioworld Technology, Inc.

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IFITM3 (interferon induced transmembrane protein 3), also known as 1-8U or IP15, is a multi-pass membrane protein that belongs to the IFITM (interferon inducible transmembrane) family of proteins. IFITM proteins are induced by type I and type II interferons and contain multiple interferon (IFN)-stimulated response elements (ISREs) in their promoter regions. IFITM proteins play important roles in many cellular processes and their expression requires the presence of the chromatin remodeling SWI/SNF-like BAF complexes. Cellular processes involving IFITM proteins include cellular anti-proliferative activities and homotypic cell adhesion functions of interferons. In addition, IFITM genes are often upregulated in various cancer cells, suggesting a possible role in carcinogenesis. Localizing to the membrane, IFITM3 is a 133 amino acid protein that is induced by IFN-alpha and IFN-gamma . IFITM3 expression can be regulated by TEF-1, Brg-1 and Sp1.

Catalogue number:	BS5762P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q01628
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide IFITM3. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Interferon-induced transmembrane protein 3; Dispanin subfamily A member 2b; DSPA2b; Interferon-inducible protein 1-8U; Fragilis
Additional info:	This peptide can be used with studies using BS5762 IFITM3 pAb.

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IFITM3 Peptide

Cat no: BS5762P

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