IGF-1R (G1155) Peptide

Cat no: BS1182P

Supplier: Bioworld Technology, Inc.

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Insulin-like growth factor-I receptor (IGF-IR) is an RTK that stimulates growth in many different cell types, blocks apoptosis, acts as an intermediate of many growth hormone responses and may stimulate the growth of some types of cancer. The IGF-IR cognate ligand insulin-like growth factor-I (IGF-I) promotes association of IGF-IR with Shc, GRB2 and Sos 1, which initiates Ras and ERK kinase cascades, thereby modifying transcription factor activity, such as activation of the Elk transcription factors. The modular phosphotyrosine binding (PTB) domains of insulin receptor substrate (IRS)-1 and -2 can associate with active IGF-IR and initiate phosphatidylinositol 3-kinase-dependent downstream signals.

Catalogue number:	BS1182P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P08069/P06213
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide IGF-1R (G1155). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Insulin-like growth factor 1 receptor; Insulin-like growth factor I receptor; IGF-I receptor; CD221; Insulin-like growth factor 1 receptor alpha chain; Insulin-like growth factor 1 receptor beta chain; IGF1R
Additional info:	This peptide can be used with studies using BS1182 IGF-1R (G1155) pAb.

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IGF-1R (G1155) Peptide

Cat no: BS1182P

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