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IL-1(alpha) pAb

Cat no: BS6919

IL-1(alpha) pAb

Two forms of interleukin-1, designated IL-1(alpha) and IL-1(beta), have been described. Although encoded by distinct genes and exhibiting roughly only 25% sequence identity, IL-1(alpha) and IL-1(beta) bind to the same receptor and seem to elicit similar biological responses. IL-1 production is generally thought to be associated with inflammation, but it has also been shown to be expressed during kidney development, thymocyte differentiation and cartilage degradation. IL-1 plays a critical role in the regulation of immune response and inflammation, acting as an activator of T and B lymphocytes and natural killer (NK) cells.

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SPECIFICATIONS

Catalog Number

BS6919

Size

100ug/100ul

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human IL-1(alpha).

Species

IL-1(alpha) pAb detects endogenous levels of IL-1(alpha) protein.

Dilutions

WB: 1:500~1:2000\nIHC: 1:50~1:200

Swiss Prot

P01583

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

~ 17 kDa

Alternative Names

IL-1A; IL1; IL1-ALPHA; IL1F1; IL1A; Interleukin-1 alpha; Hematopoietin-1;

SUPPLIER INFO

Bioworld Technology, Inc.

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