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IL-12A (T65) pAb

IL-12A (T65) pAb

Cat no: BS3490

Supplier: Bioworld Technology, Inc.
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IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-(gamma) (IFN-(gamma)). It also activates production of tumor necrosis factor (alpha) (TNF(alpha)) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-(gamma). IL-12 also has anti-angiogenic activity since the production of IFN-(gamma) increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.
Catalogue number: BS3490
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P29459
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 32-81of Human IL-12A.
Species: IL-12A (T65) pAb detects endogenous levels of IL-12A protein.
Molecular weight: ~25 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: IL12A; CLMF; IL-12A; NFSK; NKSF1
Additional info: For research use only, not for use in diagnostic procedure.

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