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IL-12A (T65) Peptide

IL-12A (T65) Peptide

Cat no: BS3490P

Supplier: Bioworld Technology, Inc.
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IL-12 is secreted by macrophages and human B-lymphoblastoid cells in response to antigenic stimulation. This IL is responsible for the differentiation of naive CD4+ T cells into type 1 helper T cells that produce interferon-gamma (IFN-gamma ). It also activates production of tumor necrosis factor alpha (TNFalpha) from T and natural killer (NK) cells, and it inhibits IL-4 mediated suppression of IFN-gamma . IL-12 also has anti-angiogenic activity since the production of IFN-gamma increases the production of inducible protein-10 (IP-10). IL-12 p40 represents a subunit of IL-12 that is induced by several pathogens. IL-12 p70 is a subunit of IL-12 that is controlled through both the p35 and p40 genes in a cell type-specific fashion.
Catalogue number: BS3490P
Applications: Block/Neutralize/Inhibit
Swiss prot: P29459
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide IL-12A (T65). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: IL12A; CLMF; IL-12A; NFSK; NKSF1
Additional info: This peptide can be used with studies using BS3490 IL-12A (T65) pAb.

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