IL-27Ralpha Peptide

Cat no: BS60331P

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

IL-27 is a heterodimeric cytokine that consists of EBI3, an IL-12p40-related protein, and p28, a IL-12p35-related polypeptide. IL-27 triggers expansion of antigen-specific naive CD4-positive T cells and promotes polarization towards a Th1 phenotype with expression of gamma-interferon. IL-27 contributes to the development of an adaptive immune response through its action on CD4-positive T cells, and also directly acts on cells of the innate immune system. IL-27 protein levels increase upon activation of antigen-presenting cells. IL-27 protein induces orphan cytokine receptor IL-27R (WSX-1)-dependent clonal expansion of naive but not memory CD4(+) T cells. IL-27 signaling through IL-27R and gp130 also induces phosphorylation of Stat1-5.

Catalogue number:	BS60331P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q6UWB1
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide IL-27Ralpha. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Interleukin-27 receptor subunit alpha; IL-27 receptor subunit alpha; IL-27R subunit alpha; IL-27R-alpha; IL-27RA; Cytokine receptor WSX-1; Cytokine receptor-like 1; Type I T-cell cytokine receptor; TCCR; ZcytoR1; IL27RA; CRL1; TCCR, WSX1; UNQ296/PRO336
Additional info:	This peptide can be used with studies using BS60331 IL-27Ralpha pAb.

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IL-27Ralpha Peptide

Cat no: BS60331P

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