IL-3Rbeta (F587) Peptide

Cat no: BS1185P

Supplier: Bioworld Technology, Inc.

0 reviews | Write a Review Pencil

Description
Additional Information

Interleukin-3, or IL-3, is a pleiotropic cytokine that is primarily secreted by activated T lymphocytes and stimulates the proliferation and differentiation of hematopoietic cells. IL-3 exerts its biological effects through a receptor which consists of a ligand-specific alpha subunit (IL-3Ralpha) and a signal transducing beta subunit (IL-3Rbeta) common to the IL-3/IL-5/GM-CSF receptors. The alpha subunits are low-affinity ligand-binding proteins while the beta subunits do not themselves bind ligand, but are required for high affinity binding by the alpha subunits. The mouse IL-3 receptor has two distinct beta subunits, one that functions only in IL-3-mediated cell signaling and a second that is shared with IL-5 and GM-CSF. The murine beta subunits are 91% homologous at the amino acid level but only 56% homologous to the human beta subunit.

Catalogue number:	BS1185P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P32927
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide IL-3Rbeta (F587). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Cytokine receptor common subunit beta; CDw131; GM-CSF/IL-3/IL-5 receptor common beta subunit; CD131; CSF2RB; IL3RB; IL5RB; IL3Rbeta
Additional info:	This peptide can be used with studies using BS1185 IL-3Rbeta (F587) pAb.

See Full Product Listings >

IL-3Rbeta (F587) Peptide

Cat no: BS1185P

Get Quote

About Biosave

Product Categories

Information


Get a Quote Direct from Bioworld Technology, Inc.




By submitting this form you agree to your details being passed to Bioworld Technology, Inc. for the purpose of generating the best quote*