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IL-4Ralpha (S254) Peptide

IL-4Ralpha (S254) Peptide

Cat no: BS3442P

Supplier: Bioworld Technology, Inc.
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IL4 Receptor alpha (IL4RA) is the alpha chain of the interleukin 4 receptor which binds to both interleukin 4 and interleukin 13 to regulate IgE production, chemokine and mucus production at sites of allergic inflammmation. The IL4 response is involved in promoting Th2 differentiation. The secreted extracellular domain of IL4R alpha, called sIL4R alpha, can inhibit IL4-mediated cell proliferation and IL5 upregulation by T-cells. It has no signaling abilities. Allelic variations in the IL4RA gene have been associated with atopy, a condition that can manifest itself as allergic rhinitis, sinusitus, asthma, or eczema.
Catalogue number: BS3442P
Applications: Block/Neutralize/Inhibit
Swiss prot: P24394
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide IL-4Ralpha (S254). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: IL4R
Additional info: This peptide can be used with studies using BS3442 IL-4Ralpha (S254) pAb.

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