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IL7 Peptide

Cat no: BS60362P

IL7 Peptide

Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene encodes a protein 177 amino acids in length. IL-7 exerts its biological function through the IL-7 receptor which is expressed on pre-B cells, thymocytes and bone marrow-derived macrophages. The IL-7 receptor is composed of an IL-7 receptor-specific chain and the IL-2 receptor gamma chain common to the IL-2, IL-4, IL-7, IL-9 and IL-15 receptors. IL-7 stimulation leads to the activation of Janus tyrosine kinase family members JAK1 and JAK3. Other studies have shown that in T cells, the IL-7 receptor-specific chain associates with the Src kinases family Lck and Fyn. IL-7 induces phosphorylation of insulin receptor substrate-1 (IRS-1) and insulin receptor substrate-2 (IRS-2), originally called 4PS.

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SPECIFICATIONS

Catalog Number

BS60362P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide IL7. (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P13232

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS60362 IL7 pAb.

Alternative Names

IL 7; IL-7; Il7; IL7; Interleukin 7; Interleukin-7;

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