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ILKAP (K71) pAb

ILKAP (K71) pAb

Cat no: BS2359

Supplier: Bioworld Technology, Inc.
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ILKAP (integrin-linked kinase-associated serine/threonine phosphatase 2C),also known as PP2C(delta), is a 392 amino acid cytoplasmic protein phosphatase
that selectively interacts with integrin linked kinase (ILK) to regulate growth factor signaling and cell adhesion. While widely expressed, ILKAP is found at highest levels in striated muscle with lower levels found in smooth muscle.ILKAP belongs to the PP2C family and contains one PP2C-like domain. ILKAP has been suggested to inhibit oncogenic transformation and the ILK-GSK3(beta)signaling axis, and can bind two magnesium or manganese ions per subunit as cofactors. The gene encoding ILKAP maps to human chromosome 2,which consists of 237 million bases encoding over 1,400 genes and making up approximately 8% of the human genome.
Catalogue number: BS2359
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunofluorescence, Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: Q9H0C8
Dilutions: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 40-90 of Human ILKAP.
Species: LKAP (K71)pAb detects endogenous levels of ILKAP protein.
Molecular weight: ~ 45 kDa
Purity: he antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: Integrin-linked kinase-associated serine/threonine phosphatase 2C; ILKAP; ILKAP
Additional info: For research use only, not for use in diagnostic procedure.

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