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Insulin Receptor (Y1355) pAb

Insulin Receptor (Y1355) pAb

Cat no: BS2985

Supplier: Bioworld Technology, Inc.
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The insulin receptor (IR) is a heterodimeric protein complex that has an intracellular (beta) subunit and an extracellular (alpha) subunit, which is disulfide- linked to a transmembrane segment. The insulin ligand binds to the IR and initiates molecular signaling pathways that promote glucose uptake in cells and glycogen synthesis. Insulin binding to IR induces phosphorylation of intracellular tyrosine kinase domains and recruitment of multiple SH2 and SH3 domain-containing intracellular proteins that serve as signaling intermediates for pleiotropic effects of insulin.
Catalogue number: BS2985
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Western Blot
Size: 100ug/100ul
Swiss prot: P06213
Dilutions: WB: 1:500~1:1000
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 1321-1370 of Human Leu-1.
Species: Insulin Receptor (Y1355) pAb detects endogenous levels of Insulin Receptor protein.
Molecular weight: ~ 95, 156 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CD 220; CD220; CD220 antigen; HHF 5; HHF5; human insulin receptor; INSR; INSR; Insulin receptor subunit beta; IR 1; IR; IR-1; IR1;
Additional info: For research use only, not for use in diagnostic procedure.

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