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Integrin (alpha)V pAb

Integrin (alpha)V pAb

Cat no: BS6891


Supplier: Bioworld Technology, Inc.
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The integrin family contains at least 18 (alpha) and 8 (beta) subunits that form 24 known integrins with distinct tissue distribution and overlaping ligand specificities. Integrins not only transmit signals to cells in response to the extracellular environment (outside-in signaling), but also sense intracellular cues to alter their interaction with extracellular environment (inside-out signaling).Several (alpha)V subfamily members, including (alpha)V(beta)3, (alpha)V(beta)5, (alpha)V(beta)1, are highly expressed in active endothelial cells and cancer cells where they play a critical role in angiogenesis and tumor metastasis.
Catalogue number: BS6891
Reactivities: Human, Mouse, Rat
Hosts: Rabbit
Applications: Immunohistochemistry, Western Blot
Size: 100ug/100ul
Swiss prot: P06756
Dilutions: WB: 1:500~1:2000 IHC: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Recombinant full length Human Integrin (alpha)V.
Species: Integrin (alpha)V pAb detects endogenous levels of Integrin (alpha)V protein.
Molecular weight: ~ 140 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CD51; MSK8; VNRA; VTNR; ITGAV
Additional info: For research use only, not for use in diagnostic procedure.

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