Integrin beta5 (V746) Peptide

Cat no: BS1188P

Supplier: Bioworld Technology, Inc.

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Integrins are heterodimers composed of noncovalently associated transmembrane alpha and beta subunits. The 16alpha and 8beta subunits heterodimerize to produce more than 20 different receptors. Most Integrin receptors bind ligands that are components of the extracellular matrix, including Fibronectin, Collagen and Vitronectin. Certain Integrins can also bind to soluble ligands such as Fibrinogen, or to counterreceptors on adjacent cells, such as the intracellular adhesion molecules (ICAMs), leading to aggregation of cells. Ligands serve to cross-link or cluster Integrins by binding to adjacent Integrin receptors; both receptor clustering and ligand occupancy are necessary for the activation of Integrinmediated responses. In addition to mediating cell adhesion and cytoskeletal organization, Integrins function as signaling receptors. Signals transduced by Integrins play a role in many ?biological processes, including cell growth, differentiation, migration and apoptosis.

Catalogue number:	BS1188P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P18084
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Integrin beta5 (V746). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Integrin beta-5; ITGB5
Additional info:	This peptide can be used with studies using BS1188 Integrin beta5 (V746) pAb.

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Integrin beta5 (V746) Peptide

Cat no: BS1188P

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