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Interferon omega, Recombinant, Human (IFN alpha II-1, IFNW1, IFN omega)

Cat no: 149745


Supplier: United States Biological
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IFN-omega is a type I interferon, which can be induced by virus-infected leukocytes. Members of the type I interferon family, which includes IFN-a, IFN-B, and IFN-w, signal through IFNAR-1/IFNAR-2 receptor complex, and exert anti-viral and anti-proliferative activities. IFN-omega exhibits about 75% sequence homology with IFN-a, and contains two conserved disulfide bonds, which are necessary for full biological activity. Recombinant Human IFN-omega is a 19.9kD protein consisting of 172aa. Source: Recombinant protein corresponding to human IFN-omega, expressed in E.coli. Biological Activity: Determined by a cytotoxicity assay using Human TF-1 cells. The ED50 was found to be 0.01ng/ml. Specific Activity: 1x10e6units/mg Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MCDLPQNHGL LSRNTLVLLH QMRRISPFLC LKDRRDFRFP QEMVKGSQLQ KAHVMSVLHE MLQQIFSLFH TERSSAAWNM TLLDQLHTGL HQQLQHLETC LLQVVGEGES AGAISSPALT LRRYFQGIRV YLKEKKYSDC AWEVVRMEIM KSLFLSTNMQ ERLRSKDRDL GSS Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 149745
Size: 20ug
Form: Supplied as a lyophilized powder.
Purity: ~98% (SDS-PAGE and HPLC)

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