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Interleukin 1 alpha (IL-1a, IL-1 alpha, Hematopoietin 1, H1, IL-1F1, Preinterleukin 1 alpha, Pro interleukin 1 alpha)

Cat no: I7663-03C

Interleukin 1 alpha (IL-1a, IL-1 alpha, Hematopoietin 1, H1, IL-1F1, Preinterleukin 1 alpha, Pro interleukin 1 alpha)

Interleukin-1alpha is a member of the interleukin 1 cytokine family. It is a pleiotropic cytokine involved in various immune responses, inflammatory processes, and hematopoiesis. This cytokine is produced by monocytes and macrophages as a proprotein, which is proteolytically processed and released in response to cell injury, and thus induces apoptosis. IL-1 alpha and eight other interleukin 1 family genes form a cytokine gene cluster on chromosome 2. It has been suggested that the polymorphism of these genes is associated with rheumatoid arthritis and Alzheimer's disease.\n\nApplications: \nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

I7663-03C

Size

100ug

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

Form

As reported

P Type

Mab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG2a

References

1. Du,Y.; et al. 2000. Neurology 55: 480-484, PubMed ID : 10953177 \n2 Grimaldi, L. et al. Ann. Neurol. 47: 361-365, 2000. PubMed ID : 10716256

Additional Info

Species Crossreactivity: Human. Other species have not been tested

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Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

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Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

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Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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