Home  >  Products  >  Interleukin 5, Recombinant, Mouse (Interleukin-5, IL-5, B-cell Growth Factor II, BCGF-II, Cytotoxic T-lymphocyte Inducer, Eosinophil Differentiation Factor, T-cell Replacing Factor, TRF, Il5)

Interleukin 5, Recombinant, Mouse (Interleukin-5, IL-5, B-cell Growth Factor II, BCGF-II, Cytotoxic T-lymphocyte Inducer, Eosinophil Differentiation Factor, T-cell Replacing Factor, TRF, Il5)

Cat no: 149700


Supplier: United States Biological
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IL-5 is a hematopoietic growth factor that stimulates the proliferation and activation of eosinophils. Produced by mast cells, T cells, and eosinophils, IL-5 plays an important role in inducing cell-mediated immunity against parasitic infections and certain tumors. Elevated levels of IL-5 lead to Eosinophilia, which may result in the induction of asthma and other allergic diseases. Human and murine IL-5 is cross-species reactive. Recombinant mouse IL-5 is a 26.2kD disulfide-linked homodimeric protein containing two 113aa chains. Source: Recombinant protein corresponding to mouse IL-5, expressed in E.coli. Biological Activity: Determined by the dose-dependent stimulation of the proliferation of human TF-1 cells. The ED50 was found to be <2ng/ml. Specific Activity: >5x10e5units/mg. Endotoxin: <0.1ng/ug (1EU/ug) AA Sequence: MEIPMSTVVK ETLTQLSAHR ALLTSNETMR LPVPTHKNHQ LCIGEIFQGL DILKNQTVRG GTVEMLFQNL SLIKKYIDRQ KEKCGEERRR TRQFLDYLQE FLGVMSTEWA MEG Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 149700
Size: 5ug
Form: Supplied as a lyophilized powder.
Purity: ~98% (SDS-PAGE and HPLC)

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