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Interleukin 9, Recombinant Human (IL-9)

Cat no: I8431

Interleukin 9, Recombinant Human (IL-9)

IL-9 is an immunoregulatory cytokine produced by IL-2 activated Th2 lymphocytes. IL-9 enhances the proliferation of T lymphocytes, mast cells, erthroid precursor cells and megakaryoblastic leukemia cell lines. Over-expression of IL-9 has been implicated in the pathogenesis of anaplastic lymphoma and Hodgkin's disease. Whereas murine IL-9 can function on human cells, human IL-9 is inactive on mouse cells. Recombinant human IL-9 is a 14.kD protein of 127 amino acid residues including 10 cysteine residues which are fully conserved between the human murine proteins.\n\nAmino Acid Sequence:\nMQGCPTLAGI LDINFLINKM QEDPASKCHC SANVTSCLCL GIPSDNCTRP CFSERLSQMT NTTMQTRYPL IFSRVKKSVE VLKNNKCPYF SCEQPCNQTT AGNALTFLKS LLEIFQKEKM RGMRGKI\n\nBiological Activity:Human IL-9 is fully biologically active when compared to standards. The ED50 was determined by the dose-dependent proliferation of human MO7e cells was (same/less than)0.2ng/ml corresponding to a specific activity of (same/more than)5x10e6u/mg.\n\nStorage and Stability: Lyophilized powder may be stored at -20 degrees C. Stable for 12 months at -20 degrees C. Reconstitute with sterile ddH2O. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

I8431

Size

2ug

Form

Supplied as a lyophilized powder with no additives. Reconstituted with sterile ddH2O to a concentration of 0.1-1.0mg/ml. Do not vortex.

Purity

(same/more than) 98% by SDS-PAGE and HPLC analyses

References

\n\n\n0.05-5.0 ng/ml

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

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Applications

IF

Hosts

Mouse

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Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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