Involucrin (P568) Peptide

Cat no: BS1189P

Supplier: Bioworld Technology, Inc.

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Involucrin is a precursor protein of the keratinocyte cornified envelope, which is formed beneath the inner surface of the cell membrane during terminal differentiation. Involucrin first appears in the cell cytosol but ultimately becomes cross-linked to membrane proteins by transglutaminase. During keratinocyte terminal differentiation glutamine residues of involucrin become covalently cross-linked to other envelope precursors via covalent E-(gamma -glutamyl) lysine bonds. Moreover, its large size allows involucrin to cross-link molecules that are separated by substantial distances in the cornified envelope. These properties allow a single involucrin molecule to form multiple cross-links, in multiple spatial planes, with other envelope precursors. Involucrin is specifically expressed in Chinese hamster ovarian cells (fibroblasts), PtK2 rat kangaroo kidney cells (simple epithelial) and rat epidermal keratinocytes (stratifying squamous epithelial).

Catalogue number:	BS1189P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P07476
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide Involucrin (P568). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	IVL
Additional info:	This peptide can be used with studies using BS1189 Involucrin (P568) pAb.

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Involucrin (P568) Peptide

Cat no: BS1189P

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