IP6K2 (L188) Peptide

Cat no: BS2759P

Supplier: Bioworld Technology, Inc.

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Description
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The members of the inositol hexakisphosphate kinase family, IP6K1 and IP6K2, have a high affinity and selectivity for inositol hexakisphosphate (InsP6) as a substrate. IP6K1 and IP6K2 (also designated PiUS) convert InsP6 to PP-InsP5. However, neither kinase demonstrates any catalytic activity with other inositol pyrophosphates. The presence of InsP6, which inhibits serine/threonine protein phosphatases, increases the influx of calcium across the plasma membrane and implies that it may mediate the regulation of insulin exocytosis. IP6K1 was purified as a 54 kDa protein in rat brain extracts. By homology, IP6K1 and IP6K2 were characterized in mouse as a 50 kDa and 49 kDa protein, respectively. IP6K1 displays ATP synthase activity by transferring a phosphate from PP-InsP5 to ADP, which suggests a role for the IP6 kinases as high energy phosphate donors.

Catalogue number:	BS2759P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q9UHH9
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide IP6K2 (L188). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Inositol hexakisphosphate kinase 2; InsP6 kinase 2; P(i)-uptake stimulator; PiUS; IP6K2; IHPK2; TCCCIA00113
Additional info:	This peptide can be used with studies using BS2759 IP6K2 (L188) pAb.

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IP6K2 (L188) Peptide

Cat no: BS2759P

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