IRF-2 (K129) Peptide

Cat no: BS1930P

Supplier: Bioworld Technology, Inc.

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Additional Information

Interferon regulatory factor-1 (IRF-1) and IRF-2 have been identified as novel DNA-binding factors that function as regulators of both type I interferon (interferon-alpha and beta) and interferon-inducible genes. The two factors are structurally related, particularly in their N-terminal regions, which confer DNA binding specificity. In addition, both bind to the same sequence within the promoters of interferon-alpha and interferon-beta genes. IRF-1 functions as an activator of interferon transcription, while IRF-2 binds to the same cis elements and represses IRF-1 action. IRF-1 and IRF-2 have been reported to act in a mutually antagonistic manner in regulating cell growth; overexpression of the repressor IRF-2 leads to cell transformation while concomitant overexpression of IRF-1 causes reversion. IRF-1 and IRF-2 are members of a larger family of DNA binding proteins that includes IRF-3, IRF-4, IRF-5, IRF-6, IRF-7, ISGF-3gamma p48 (the 48 kDa component of the ISGF-3 complex) and IFN consensus sequence-binding protein (ICSBP).

Catalogue number:	BS1930P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P14316
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide IRF-2 (K129). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	IRF-2; IRF2; IRF-2
Additional info:	This peptide can be used with studies using BS1930 IRF-2 (K129) pAb.

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IRF-2 (K129) Peptide

Cat no: BS1930P

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