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IRF-4 (Y294) Peptide

Cat no: BS2659P

IRF-4 (Y294) Peptide

Transcriptional activator. Binds to the interferon-stimulated response element (ISRE) of the MHC class I promoter. Binds the immunoglobulin lambda light chain enhancer, together with PU.1. Probably plays a role in ISRE-targeted signal transduction mechanisms specific to lymphoid cells. Involved in CD8+ dendritic cell differentiation by forming a complex with the BATF-JUNB heterodimer in immune cells, leading to recognition of AICE sequence (5'-TGAnTCA/GAAA-3'), an immune-specific regulatory element, followed by cooperative binding of BATF and IRF4 and activation of genes

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SPECIFICATIONS

Catalog Number

BS2659P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide IRF-4 (Y294). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q15306

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2659 IRF-4 (Y294) pAb.

Alternative Names

IRF4; IRF-4; LSIRF; MUM1; NF-EM5

SUPPLIER INFO

Bioworld Technology, Inc.

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