Jagged1 (JAG1, AGS, AHD, AWS, HJ1, JAGL1, Alagille Syndrome Protein, CD339, Headturner, Htu, MGC104644, Serrate-1, Ser-1, Slalom)

Cellular Localization: Type I membrane protein.\n\nApplications: \nSuitable for use in ELISA (peptide) and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

J0400-01F

Size

500ug

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

0.01% Sodium Azide

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Proweller A et al. Notch signaling represses myocardin-induced smooth muscle cell differentiation. J Biol Chem : (2005). <PUBMED:15634680>Mancini SJ et al. Jagged1 dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. Blood : (2004). <PUBMED:15550486>Stidworthy MF et al. Notch1 and Jagged1 are expressed after CNS demyelination, but are not a major rate-determining factor during remyelination. Brain 127:1928-41 (2004). <PUBMED:15289265>Kostyszyn B et al. Distribution of presenilin 1 and 2 and their relation to Notch receptors and ligands in human embryonic/foetal central nervous system. Brain Res Dev Brain Res 151:75-86 (2004). <PUBMED:15246694>

Additional Info

Species Crossreactivity: Expected to crossreact with Human (100% identity with immunogen), Mouse (100% identity with immunogen) and Rat (100% identity with immunogen) due to sequence homology.