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JunB (G73) Peptide

JunB (G73) Peptide

Cat no: BS1197P


Supplier: Bioworld Technology, Inc.
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The c-Jun proto-oncogene was first identified as the cellular homolog of the avian sarcoma virus v-Jun oncogene. The c-Jun protein along with c-Fos is a component of the AP-1 transcriptional complex. c-Jun can form either Jun/Jun homodimers or Jun/Fos heterodimers via the leucine repeats in both proteins. Homo- and heterodimers bind to the TGACTCA consensus sequence present in numerous promoters and initially identified as the phorbol ester tumor promoter response element (TRE). Two additional genes, Jun B and Jun D have been shown to be almost identical to c-Jun in their C-terminal regions, which are involved in dimerization and DNA binding, whereas their N-terminal domains, which are involved in transcriptional activation, diverge. All three form heterodimers among themselves and with c-Fos and other members of the Fos gene family
Catalogue number: BS1197P
Applications: Block/Neutralize/Inhibit
Swiss prot: P17275
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide JunB (G73). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: JunB; Jun B; Jun B proto oncogene; Transcription factor jun-B
Additional info: This peptide can be used with studies using BS1197 JunB (G73) pAb.

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