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Kaiso (Zinc Finger and BTB Domain Containing 33, ZBTB33)

Cat no: K0004-02

Kaiso (Zinc Finger and BTB Domain Containing 33, ZBTB33)

Kaiso is a transcriptional represor that belongs to POZ-zinc finger family of transcription factors implicated in development and cancer. It binds to specific methylated CpG dinucleotides in the consensus sequence 5'-CGCG-3' and it also binds to non-methylated consensus sequence 5'-CTGCNA-3'. It recruits the N-CoR repressor complex to promote histone deacetylation and the formation of represive chromatin structures in taget gene promoters. Kaiso may contribute to the repression of target genes of the Wnt signaling pathway.\n\nKaiso is a novel member of the BTB/POZ (Broad complex, Tramtrak, Bric

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SPECIFICATIONS

Catalog Number

K0004-02

Size

100ug

Applications

IF, IP, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Can, Ch/Bird

Form

PBS

P Type

Mab

Purity

Purified

Isotype

IgG1

References

This clone has been used inRodova M et al. Regulation of the rapsyn promoter by kaiso and delta-catenin. Mol Cell Biol 247188-96 (2004). <PUBMED15282317>Daniel JM et al. Monoclonal antibodies to Kaiso a novel transcription factor and p120ctn-binding protein. Hybridoma 20159-66 (2001). <PUBMED11461664>

Additional Info

Species Crossreactivity: Crossreacts with Human, Mouse, Rat, Chicken, canine and Hamster. Not yet tested in other species.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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