KCNS3, NT (KCNS3, Potassium voltage-gated channel subfamily S member 3, Delayed-rectifier K(+) channel alpha subunit 3, Voltage-gated potassium channel subunit Kv9.3) (APC)

Voltage-gated potassium channels form the largest and most diversified class of ion channels and are present in both excitable and nonexcitable cells. Their main functions are associated with the regulation of the resting membrane potential and the control of the shape and frequency of action potentials. The alpha subunits are of 2 types: those that are functional by themselves and those that are electrically silent but capable of modulating the activity of specific functional alpha subunits. The protein encoded by this gene is not functional by itself but can form heteromultimers with member 1 and with member 2 (and possibly other members) of the Shab-related subfamily of potassium voltage-gated channel proteins. This gene belongs to the S subfamily of the potassium channel family.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze APC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

037349-APC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to Allophycocyanin (APC).

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Nyholt, D.R., et al. Hum. Mol. Genet. 17(21):3318-3331(2008)\nvan Es, M.A., et al. Nat. Genet. 40(1):29-31(2008)\nSchymick, J.C., et al. Lancet Neurol 6(4):322-328(2007)\nGutman, G.A., et al. Pharmacol. Rev. 57(4):473-508(2005)\nKerschensteiner, D., et al. Proc. Natl. Acad. Sci. U.S.A. 102(17):6160-6165(2005)

Additional Info

Human

Alternative Names

KCNS3, Potassium voltage-gated channel subfamily S member 3, Delayed-rectifier K(+) channel alpha subunit 3, Voltage-gated potassium channel subunit Kv9.3