KDM5C (C-terminus) mAb

This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants.

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SPECIFICATIONS

Catalog Number

MB0076

Size

100ug/100ul

Applications

WB

Hosts

Mouse

Reactivities

Hum

Form

liquid

Purity

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Synthetic peptide, corresponding to amino acids N-terminus of Human KDM5C.

Species

This antibody detects endogenous levels of KDM5C (C-terminus) and does not cross-react with related proteins

Dilutions

WB: 1:1000\nICC: 1:100~200

Swiss Prot

P41229

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

Predicted band size:176KDa \nObserved band size:220KDa

Alternative Names

MRXJ; SMCX; MRXSJ; XE169; MRXSCJ; JARID1C; DXS1272E; Lysine-specific demethylase 5C; Histone demethylase JARID1C; Jumonji/ARID domain-containing protein 1C