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KKIAMRE (L240) Peptide

KKIAMRE (L240) Peptide

Cat no: BS2113P

Supplier: Bioworld Technology, Inc.
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The activation of signal transduction pathways by growth factors, hormones and neurotransmitters is mediated by the MAP kinases ERK 1 and ERK 2. ERK proteins are regulated by dual phosphorylation at specific tyrosine and threonine sites mapping within a characteristic Thr-Glu-Tyr motif. The protein kinase p56 KKIAMRE is distantly related to the MAP kinase group of proteins and is closely related to p42 KKIALRE. KKIAMRE is predominantly expressed in testis, kidney, brain and lung. KKIAMRE contains the conserved MAP kinase dual phosphorylation motif in the sequence Thr-Asp-Tyr and is activated by treatment of cells by EGF. However, unlike other MAP kinases, the EGF-stimulated kinase activity does not require phosphorylation of KKIAMRE and KKIALRE in the Thr-Asp-Tyr motif.
Catalogue number: BS2113P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q92772
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide KKIAMRE (L240). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: Cyclin-dependent kinase-like 2; Serine/threonine-protein kinase KKIAMRE; Protein kinase p56 KKIAMRE; CDKL2;
Additional info: This peptide can be used with studies using BS2113 KKIAMRE (L240) pAb.

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