KSR (R386) Peptide

Cat no: BS1707P

Supplier: Bioworld Technology, Inc.

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Several serine/threonine protein kinases have been implicated as intermediates in signal transduction pathways. These include ERK/MAP kinases, ribosomal S6 kinase (Rsk) and Raf-1. Raf-1 has intrinsic kinase activity towards serine/threonine residues and is widely expressed in many tissue types and cell lines. Raf-1 activation is dependent on the small molecular weight GTPase Ras, but the means by which this activation occurs is poorly understood. Two proteins putatively involved in this process are Ksr-1 and Tak1. Ksr-1 (kinase suppressor of Ras) is a novel Raf-related protein kinase whose function is required for Ras signal transduction. Whether Ksr-1 lies directly downstream of Ras or acts in a parallel pathway is not yet known. Tak1 (TGFb-activated kinase) has been shown to participate in the activation of the MAP kinase family in response to TGFb stimulation.

Catalogue number:	BS1707P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	Q8IVT5
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide KSR (R386). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	BKSR 1; BKSR1; dKsr; EK 31; EK31; hb; Kinase suppressor of ras 1; Kinase suppressor of ras; KSR 1; KSR; KSR1; Positive Ras signaling mediator family member (86.4 kD); Positive Ras signaling mediator family member; RSU 2; RSU2; SR 31; SR31;
Additional info:	This peptide can be used with studies using BS1707 KSR (R386) pAb.

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KSR (R386) Peptide

Cat no: BS1707P

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