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Ksr2 (I694) Peptide

Ksr2 (I694) Peptide

Cat no: BS2321P

Supplier: Bioworld Technology, Inc.
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Kinase suppressor of Ras (Ksr) and MAP kinase kinase kinase (MEKK3) are integral members of the MAP kinase pathway. Ksr is a conserved protein that positively regulates Ras signaling and may function as a scaffold for Raf, MEK and ERK. There are two types of Ksr proteins: Ksr-1 and Ksr-2. Ksr-2 plays a key role in Ras-mediated signaling during germline meiotic progression and functions redundantly with Ksr-1 during the development of the excretory system pathway, hermaphrodite vulva, and male spicules. Ksr-2 also functions as a negative regulator of the MEKK3-mediated activation of the MAP kinase pathways (specifically ERK and JNK) and of the NF?B pathways, and it simultaneously inhibits MEKK3-mediated Il-8 production.
Catalogue number: BS2321P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q6VAB6
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Ksr2 (I694). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: KSR2; Kinase suppressor of Ras 2
Additional info: This peptide can be used with studies using BS2321 Ksr2 (I694) pAb.

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