Ku-70 (R586) pAb

Cat no: BS1212

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.

Catalogue number:	BS1212
Reactivities:	Human, Mouse, Rat
Hosts:	Rabbit
Applications:	Immunofluorescence, Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P12956
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 560-600 of Human Ku-70.
Species:	Ku70 (R586) pAb detects endogenous levels of Ku70 protein.
Molecular weight:	~ 70 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	XRCC6; CTC75; CTCBF; D22S671; D22S731; EC 3.6.1.-; G22P1; KU70; ML8; TLAA
Additional info:	For research use only, not for use in diagnostic procedure.

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Ku-70 (R586) pAb

Cat no: BS1212

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