Ku-86 (A717) pAb

Cat no: BS1497

Supplier: Bioworld Technology, Inc.

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Description
Additional Information

The Ku protein is localized in the nucleus and is composed of subunits referred to as Ku-70 (or p70) and Ku-86 (or p86), which is also known by the synonym Ku-80 (or p80). Ku was first described as an autoantigen to which antibodies were produced in a patient with scleroderma-polymyositis overlap syndrome, and was later found in the sera of patients with other rheumatic diseases. Both subunits of the Ku protein have been cloned, and a number of functions have been proposed for Ku, including cell signaling, DNA replication and transcriptional activation.

Catalogue number:	BS1497
Reactivities:	Human, Mouse
Hosts:	Rabbit
Applications:	Immunohistochemistry, Western Blot
Size:	100ug/100ul
Swiss prot:	P13010
Dilutions:	WB: 1:500~1:1000 IHC: 1:50~1:200
Form:	liquid
Storage buffer:	1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration:	1ug/ul
Antigen:	Synthetic peptide, corresponding to amino acids 700-730 of Human Ku-86.
Species:	XRCC5 (A717) pAb detects endogenous levels of XRCC5 protein.
Molecular weight:	~ 70,82 kDa
Purity:	The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp:	Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names:	CTC box-binding factor 85 kDa subunit; CTCBF; CTC85; Nuclear factor IV; DNA-repair prote; XRCC5; KARP-1. KARP1. KU80. Ku86. NFIV
Additional info:	For research use only, not for use in diagnostic procedure.

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Ku-86 (A717) pAb

Cat no: BS1497

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