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Laminin alpha-4 (A511) Peptide

Laminin alpha-4 (A511) Peptide

Cat no: BS2531P


Supplier: Bioworld Technology, Inc.
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Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cellassociated extracellular matrices (ECMs)) are polymers of laminins with stabilizing type IV collagen networks, nidogen, and several proteoglycans.Basement membranes are found under epithelial layers, around the endothelium of blood vessels, and surrounding muscle, peripheral nerve, and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression, and tissue architecture. Each laminin is a heterotrimer of alpha, beta, and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble, bind to other matrix macromolecules, and have unique and shared cell interactions mediated by integrins, dystroglycan, and cognate laminin receptors. The human laminin alpha-4 gene maps to chromosome 6q21 and is expressed in adult heart, lung, ovary, small and large intestines, liver, and placenta.
Catalogue number: BS2531P
Applications: Block/Neutralize/Inhibit
Swiss prot: Q16363
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Laminin alpha-4 (A511). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: LAMA4
Additional info: This peptide can be used with studies using BS2531 Laminin alpha-4 (A511) pAb.

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