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Laminin beta-1 (D1742) Peptide

Cat no: BS2415P

Laminin beta-1 (D1742) Peptide

Laminins are essential and abundant structural non-collagenous glycoproteins localizing to basement membranes. Basement membranes (cell-associated extracellular matrices (ECMs)) are polymers of Laminins with stabilizing type IV collagen networks, nidogen and several proteoglycans. Basement membranes are found under epithelial layers, around the endothelium of blood vessels and surrounding muscle, peripheral nerve and fat cells. Formation of basement membranes influences cell proliferation, phenotype, migration, gene expression and tissue architecture. Each Laminin is a heterotrimer of alpha, beta and gamma chain subunits that undergoes cell-secretion and incorporation into the ECM. Laminins can self-assemble and bind to other matrix macromolecules, and have unique and shared cell interactions mediated by Integrins, dystroglycan and cognate Laminin receptors. The human Laminin gamma -1 gene maps to chromosome 1q31 and is ubiquitously expressed in tissues that produce basement membranes.

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SPECIFICATIONS

Catalog Number

BS2415P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Laminin beta-1 (D1742). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P07942

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2415 Laminin beta-1 (D1742) pAb.

Alternative Names

LAMA1; LAMA

SUPPLIER INFO

Bioworld Technology, Inc.

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