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LHX1 Peptide

LHX1 Peptide

Cat no: BS5782P

Supplier: Bioworld Technology, Inc.
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During development, genetically distinct subtypes of motor neurons express unique combinations of LIM-type homeodomain factors, which regulate cell migration and guide motor axons to establish the fidelity of a binary choice in axonal trajectory. The LIM gene family encodes a set of gene products, which carry the LIM domain, a unique cysteine-rich zinc-binding domain. At least 40 members of this family have been identified in vertebrates and invertebrates, and are distributed into 4 groups according to the number of LIM domains and to the presence of homeodomains and kinase domains. The overlapping expression of LHX1, LHX3, LHX4, Isl-1 and Isl-2 in developing motorneurons along the spinal column may influence the establishment of specific motorneuron subtypes. The human LHX1 gene maps to chromosome 11p13-p12 and encodes a 384 amino acid protein. The human LHX1 transcript is assembled from five exons, which are separated by introns ranging in size from 93 nt to 2.3 kb. The two LIM domains are entirely contained in the first and second exons, respectively, while the homeodomain is split into exons three and four.
Catalogue number: BS5782P
Applications: Block/Neutralize/Inhibit
Swiss prot: P48742
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide LHX1. (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: LIM/homeobox protein Lhx1; LIM homeobox protein 1; Homeobox protein Lim-1; hLim-1; LIM-1; LIM1; LHX-1
Additional info: This peptide can be used with studies using BS5782 LHX1 pAb.

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