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LIMK2 (K491) Peptide

LIMK2 (K491) Peptide

Cat no: BS2284P

Supplier: Bioworld Technology, Inc.
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Proteins containing LIM motifs are typically involved in cell fate determination and growth control. A family of proteins designated LIM kinases, including LIMK-1 and LIMK-2, has been identified. LIMK-1 has been shown to regulate the stabilization of F-Actin structures and cofilin activity, indicating that LIMK-1 plays a role in a signaling pathway involved in the regulation of cell motility and morphogenesis. LIMK-1 inhibits neuronal differentiation of PC12 cells, and is thought to act by interfering with events downstream of MAPK activation. Expression patterns of LIMK-1 and LIMK-2 suggest that these proteins may have different functions during development. A truncated form of LIMK-2 has been identified in adult testis that is thought to arise from an alternative initiation exon.
Catalogue number: BS2284P
Applications: Block/Neutralize/Inhibit
Swiss prot: P53671
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide LIMK2 (K491). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: LIM domain kinase 2; LIMK 2; LIMK2
Additional info: This peptide can be used with studies using BS2284 LIMK2 (K491) pAb.

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