LRP, MVP (Lung Resistance-related Protein, Major Vault Protein, VAULT 1, VAULT1)

Applications:\nSuitable for use in Immunohistochemistry and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry (frozen, paraffin): 1:20-50 \nWestern Blot: 1:50 \nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

L4500-03J

Size

1ml

Applications

IHC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in 0.7% BSA, 0.1% sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG2b

References

1.Schroeijers AB et al., In: Thesis Schroeijers AB, Chapter 4: 2000a; 2.Schroeijers AB et al., Cancer Res. 60: 1104, 2000b; 3.Kickhoefer VA et al., J. Cell Biol. 146: 917, 1999; 4.Kickhoefer VA et al., J. Bio. Chem. 273: 8971, 1998; 5.Scheper RJ et al., Cancer Res. 53: 1475, 1993; 6.Scheffer GL et al, Nature Med. 1: 578, 1995; 7.Izquierdo MA et al., Cytotechnology 27: 137, 1998.\n

Additional Info

Recognizes an internal epitope of MVP/LRP (p110), which is strongly overexpressed in various human non-P-glycoprotein MDR tumor cell lines, accordingly to an increase in the number of vault particles.

Alternative Names

2310009M24Rik