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LRRFIP1 mAb

Cat no: MB0034

LRRFIP1 mAb

Transcriptional repressor which preferentially binds to the GC-rich consensus sequence (5'-AGCCCCCGGCG-3') and may regulate expression of TNF, EGFR and PDGFA. May control smooth muscle cells proliferation following artery injury through PDGFA repression. May also bind double-stranded RNA. Positively regulates Toll-like receptor (TLR) signaling in response to agonist probably by competing with the negative FLII regulator for MYD88-binding.

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SPECIFICATIONS

Catalog Number

MB0034

Size

100ug/100ul

Applications

WB

Hosts

Mouse

Reactivities

Hum, Mouse

Form

liquid

Purity

The antibody was affinity-purified from mouse ascites by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).

Antigen

Recombinant full length Human LRRFIP1.

Species

This antibody detects endogenous levels of LRRFIP1 and does not cross-react with related proteins

Dilutions

WB: 1:1000

Swiss Prot

Q32MZ4

Storage Temp

Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.

Concentration

1ug/ul

Storage Buffer

1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.

Additional Info

For research use only, not for use in diagnostic procedure.

Molecular Weight

Predicted band size:89KDa\nObserved band size:160KDa

Alternative Names

GC-binding factor 2; TAR RNA-interacting protein; GCF2; TRIP; FLAP1; GCF-2; FLAP-1; HUFI-1; FLIIAP1

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