Lsk (V157) Peptide

For instance, a mutant of c-Src, in which Y527 is replaced by phenylalanine, is transforming and displays 5 to 10-fold elevated kinase activity compared to its normal counterpart. Csk has been identified as a Src related tyrosine kinase having both SH2 and SH3 domains and a catalytic domain but lacking sequences amino terminal to the SH3 domain as well as the carboxy-terminal regulatory sequences. Csk phosphorylates Src on Y527 and also down regulates Lyn, Fyn and Lck by tyrosine phosphorylation of carboxy-terminal regulatory sites. A Csk-like protein- tyrosine kinase of mouse origin (Ctk), also designated Ntk, and its human homolog, Lsk, have also been described.

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SPECIFICATIONS

Catalog Number

BS9181P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Lsk (V157). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P42679

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS9181 Lsk (V157) pAb.

Alternative Names

LCK; Lck p56; LCK; Leukocyte C-terminal Src kinase; LSK; Lymphocyte cell specific protein tyrosine kinase; Lymphocyte cell-specific protein-tyrosine kinase; Lymphocyte Specific Protein Tyrosine Kinase; Membrane associated protein tyrosine kinase; Oncogene lck; P56 LCK; p56(LSTRA) protein tyrosine kinase; p56-LCK; p56lck; pp58 lck; pp58lck; Protein YT16; Proto oncogene tyrosine protein kinase LCK; Proto-oncogene Lck; Protooncogene tyrosine protein kinase LCK; T cell spec