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LT-beta (V211) Peptide

Cat no: BS2038P

LT-beta (V211) Peptide

Tumor necrosis factor (TNF) and lymphotoxin-alpha (LT-alpha, also known as TNF?beta) are members of a family of secreted and cell surface cytokines that participate in the regulation of immune and inflammatory responses. LT-beta (lymphotaxin-beta or tumor necrosis factor C) is a type II membrane protein with significant homology to TNF, LT-alpha, and the ligand for the CD40 receptor. LT-alpha is present on the surface of activated T, B, and LAK cells as a complex with the 33 kda glycoprotein, LT-beta. LT-beta, also expressed by active lymphocytes, forms a heterotrimer with LT-a on the cell surface and anchors LT-alpha to the cell surface. A TNF receptor-related protein, the LT-beta receptor (also known as TNFC receptor), is the human receptor for the LT-alpha/LT-beta heterotrimer. There are two LT-beta isoforms expressed in human lymphoid cell lines and non-Hodgkin's lymphomas. The gene which encodes LT-beta maps to the major histocompatibility complex region on human chromosome 6p21.3.

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SPECIFICATIONS

Catalog Number

BS2038P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide LT-beta (V211). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

Q06643

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using BS2038 LT-beta (V211) pAb.

Alternative Names

LTA; LT; LT-ALPHA; TNF-BETA; TNFB; TNFSF1

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