LY6E, ID (LY6E, 9804, RIGE, SCA2, TSA1, Lymphocyte antigen 6E, Retinoic acid-induced gene E protein, Stem cell antigen 2, Thymic shared antigen 1) (FITC)

Sca1, also known as Ly6A/E, is a member of the Ly6 multigene family of type V glycophosphatidylinositol anchored cell surface proteins. It is expressed on multipotent hematopoietic stem cells in bone marrow of mice with both the Ly6.1 and Ly6.2 allotypes. In the periphery, Sca1 exhibits a pattern of expression which is based on differences between the two allotypes. Ly6.1 strains (e.g., A, BALB/c, CBA, C3H/He, DBA/1, NZB) have few Sca1+ resting peripheral lymphocytes, whereas Ly6.2 strains (e.g., AKR, C57BL, C57BR, C57L, DBA/2, PL, SJL, SWR, 129) have relatively high numbers of Sca1+ lymphocytes. The expression of Sca1 is dramatically upregulated in all strains upon cellular activation.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Do not freeze FITC conjugates. Light sensitive. Aliquots are stable for 6 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

038014-FITC

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. Contains ~0.09% sodium azide. Conjugated to FITC.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Davila, S., et al. Genes Immun. 11(3):232-238(2010)\nWang, J.L., et al. Mov. Disord. 24(13):2007-2011(2009)\nSocal, M.P., et al. Parkinsonism Relat. Disord. 15(5):374-378(2009)\nTang, J., et al. Lupus 17(9):805-813(2008)\nWang, A.G., et al. Biochem. Biophys. Res. Commun. 345(3):1022-1032(2006)

Additional Info

Human

Alternative Names

LY6E, 9804, RIGE, SCA2, TSA1, Lymphocyte antigen 6E, Retinoic acid-induced gene E protein, Stem cell antigen 2, Thymic shared antigen 1