Lycopene is a phytochemical, synthesized by plants and microorganisms but not by animals. It is an acyclic isomer of beta-carotene. This highly unsaturated hydrocarbon contains 11 conjugated and 2 unconjugated double bonds, making it longer than any other carotenoid. As a polyene, it undergoes cis-trans isomerization induced by light, thermal energy, and chemical reactions. Lycopene obtained from plants tends to exist in an all-trans configuration, the most thermodynamically stable form. Humans cannot produce lycopene and must ingest fruits, absorb the lycopene, and process it for use in the body. In human plasma, lycopene is present as an isomeric mixture, with 50% as cis isomers.
Solubility:
Chloroform
Stability:
Hygroscopic, light and moisture sensitive. Unstable in solution.
Atmosphere:
Inert gas
Melting Point:
162-164C
Method for Determining Identity:
Proton NMR Spectroscopic and Mass Spectrometric Analysis
TLC Conditions:
SiO2: Hexane; Ethyl Aectate: 10:1; Visualized with UV and naked eye; Single spot; Rf=0.6
Storage:
Long-term storage is recommended at -70 degrees C. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Store under inert atmosphere.
Toxicity and Hazards:
Due to the potential danger associated with the use of some of United States Biological biochemicals, all products should be handled by qualified personnel only, trained in laboratory procedures, and familiar with potential hazards. Information is not available on the possible hazards of many experimental compounds. The absence of a warning must not be interpreted as indication of safety. The ultimate responsibility for the proper handling of any and all chemicals lies with the user. All goods sold by United States Biological carry the condition that liability for any injury, loss or damage whatsoever to persons or real property resulting from the handling of the said goods lies with the user. Acceptance of our goods binds the customer to these terms.