M2A Antigen (Lymphatic Endothelial Cell Marker)

This antibody recognizes the M2A oncofetal antigen, a 40kd MWt, O-linked sialoglycoprotein, expressed on the cell membrane of lymphatic endothelium, fetal gonocytes and certain germ cell tumor cell lines. No reactivity is seen on cancer cell lines of human breast, prostate, melanoma, cervix, colon, pharynx, brain and bone marrow. This antibody has also been shown to be a useful marker for cells of mesothelial origin, including malignant mesothelioma. This antibody will be helpful in identifying tissues expressing the M2A antigen.\n\nApplications: \nSuitable for use in Immunohistochemistry. Other applications not tested.\n\nRecommended Dilution:\nImmunohistochemistry: 1:40 for 1 hr at RT\nOptimal dilutions to be determined by the researcher.\n\nPositive Control: \nColon submucosa\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

M0920

Size

500ul

Applications

IHC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a buffered solution in 15mM sodium azide.

P Type

Mab

Purity

Supernatant

Isotype

IgG1

References

1.Marks, A. et al (1999). Characterization and distribution of an oncofetal antigen (M2A antigen) expressed on testicular germ cell tumours. Br. J. Cancer 80:569-578. 2.Kahn, H.J., Bailey, D., Marks, A. (2002). Monoclonal antibody D2-40, a new marker of lymphatic endothelium, reacts with Kaposi

Additional Info

Recognizes human M2A Antigen.