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mAChR M5 (L321) pAb

mAChR M5 (L321) pAb

Cat no: BS2782

Supplier: Bioworld Technology, Inc.
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The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.
Catalogue number: BS2782
Reactivities: Human
Hosts: Rabbit
Applications: Immunofluorescence, Western Blot
Size: 100ug/100ul
Swiss prot: P08912
Dilutions: WB: 1:500~1:1000 IF: 1:50~1:200
Form: liquid
Storage buffer: 1 mg/ml in Phosphate buffered saline (PBS) with 0.05% sodium azide, approx. pH 7.2.
Concentration: 1ug/ul
Antigen: Synthetic peptide, corresponding to amino acids 291-340 of Human mAChR M5.
Species: mAChR M5 (L321) pAb detects endogenous levels of mAChR M5 protein.
Molecular weight: ~ 60 kDa
Purity: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE).
Storage temp: Store at 4 degrees C short term. Aliquot and store at -20 degrees C long term. Avoid freeze-thaw cycles.
Alternative names: CHRM5; Muscarinic acetylcholine receptor M5
Additional info: For research use only, not for use in diagnostic procedure.

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