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mAChR M5 (L321) Peptide

mAChR M5 (L321) Peptide

Cat no: BS2782P


Supplier: Bioworld Technology, Inc.
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The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of phosphoinositides and modulation of potassium channels. The mAChRs transducer signals by coupling to G-proteins, which then modulate several downstream effector proteins and ion channels. Five mAChR subtypes have been identified, designated M1 to M5. The five receptor subtypes show distinct patterns of tissue distribution, as well as distinct pharmacological and functional properties. The amino acid sequence of each mAChR subtype reflects a structure that is characteristic of G-protein coupled receptors, consisting of seven highly conserved transmembrane segments and a large intracellular region unique to each subtype, which constitutes the effector-coupling domain.
Catalogue number: BS2782P
Applications: Block/Neutralize/Inhibit
Swiss prot: P08912
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide mAChR M5 (L321). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: CHRM5; Muscarinic acetylcholine receptor M5
Additional info: This peptide can be used with studies using BS2782 mAChR M5 (L321) pAb.

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