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Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (APC)

Cat no: M1201-21A

Macrophage Colony Stimulating Factor Receptor (M-CSFR, CSF-1) (APC)

M-CSF R (macrophage colony stimulating factor receptor, c-fms) is a 165kD, 977aa type I membrane glycoprotein. It is a member of the type III subfamily of receptor tyrosine kinases that contain five extracellular immunoglobulin-like domains and a cytosolic split kinase domain. M-CSF receptor is expressed primarily on monocytes, macrophages, dendritic cells, and stem cells, and regulates lineage decisions and maturation of these cells. The mouse M-CSF R extracellular domain shares >99% aa identity with rat and 60-63% aa identity with human, dog, cat and cow M-CSF R. It can be released by TACE/ADAM17 cleavage.\n\nApplications: \nSuitable for use in Flow Cytometry. Other applications not tested.\n\nRecommended Dilution:\nFlow Cytometry: 10ul labels 1-2.5 x 10e5 cells\nOptimal dilutions to be determined by the researcher.\n\nHybridoma: \nMouse myeloma cells with B cells from a rat immunized with purified NS0-derived recombinant mouse M-CSF R (aa20-511).\n\nStorage and Stability:\nMay be stored at 4 degrees C before opening. DO NOT FREEZE! Stable at 4 degrees C. Stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. Freezing APC conjugates will result in a substantial loss of enzymatic activity. APC conjugates are sensitive to light.

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SPECIFICATIONS

Catalog Number

M1201-21A

Size

100Tests

Applications

FC

Hosts

Rat

Reactivities

Mouse

Form

Supplied as a liquid in saline, 0.1% sodium azide, 0.5% BSA. Labeled with Labeled with Allophycocyanin (APC).

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG2B

Additional Info

Recognizes mouse Macrophage Colony Stimulating Factor Receptor.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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