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Mal (s111) Peptide

Cat no: AP0684P

Mal (s111) Peptide

MAL (myelin and lymphocyte protein), also known as T lymphocyte maturation-associated protein, is a nonglycosylated hydrophobic integral membrane protein belonging to the Myelin and lymphocyte (MAL) family of proteolipids. MAL is highly enriched in nervous system myelin and in rafts and apical membranes of epithelial cells. It is involved in forming, stabilizing and maintaining glycosphingolipid-enriched membrane microdomains. MAL maintains the myelin sheath and, by controlling the sorting and trafficking of oligodendrocytes, it is involved in central nervous system paranode maintenance. MAL is a component of lipid rafts in myelinating cells. Association with glycosphingolipids may result in protein-lipid microdomain formation in myelin. MAL has been localized to the endoplasmic reticulum of T cells and in compact myelin of cells in the nervous system. MAL is primarily expressed by oligodendrocytes and Schwann cells in the intermediate and late stages of T cell differentiation.

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SPECIFICATIONS

Catalog Number

AP0684P

Applications

BNI

Form

1 mg/ml in DI water.

Purity

Synthetic peptide Mal (s111). (Note: the amino acid sequence is proprietary). The purity is > 98%.

Swiss Prot

P21145

Storage Temp

Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.

Additional Info

This peptide can be used with studies using AP0684 Mal (s111) pAb.

Alternative Names

MAL; Myelin and lymphocyte protein; T-lymphocyte maturation-associated protein

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