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Malic enzyme 1 (Y500) Peptide

Malic enzyme 1 (Y500) Peptide

Cat no: BS3886P

Supplier: Bioworld Technology, Inc.
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ME1 (Malic enzyme 1), also known as NADP-ME, MES or HUMNDME, is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family. Expressed ubiquitously with highest expression in liver and white adipose tissue, ME1 functions as an NADP-dependent enzyme that catalyzes the conversion of S-malate and NADP to pyruvate, carbon dioxide and NADPH (a reducing agent that participates in fatty acid biosynthesis). Through its ability to catalyze the reversible oxidative decarboxylation of malate, ME1 links the citric acid and glycolytic cycles. ME1 exists as a homotetramer that uses divalent metal cations, such as magnesium or manganese, as cofactors. The expression of ME1 is regulated by both thyroid hormone levels and the amount of carbohydrates in the diet, indicating that ME1 may play an important role as a housekeeping protein within the cell.
Catalogue number: BS3886P
Applications: Block/Neutralize/Inhibit
Swiss prot: P48163
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide Malic enzyme 1 (Y500). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: malic enzyme 1; NADP(+)-dependent; cytosolic; HUMNDME; MES
Additional info: This peptide can be used with studies using BS3886 Malic enzyme 1 (Y500) pAb.

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