MAP-2 (W14) Peptide

Cat no: BS3487P

Supplier: Bioworld Technology, Inc.

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MAP2 is the major microtubule associated protein of brain tissue. There are three forms of MAP2; two are similarily sized with apparent molecular weights of 280 kDa (MAP2a and MAP2b) and the third with a lower molecular weight of 70 kDa (MAP2c). In the newborn rat brain, MAP2b and MAP2c are present, while MAP2a is absent. Between postnatal days 10 and 20, MAP2a appears. At the same time, the level of MAP2c drops by 10-fold. This change happens during the period when dendrite growth is completed and when neurons have reached their mature morphology. MAP2 is degraded by a Cathepsin D-like protease in the brain of aged rats. There is some indication that MAP2 is expressed at higher levels in some types of neurons than in other types. MAP2 is known to promote microtubule assembly and to form side-arms on microtubules. It also interacts with neurofilaments, actin, and other elements of the cytoskeleton.

Catalogue number:	BS3487P
Applications:	Block/Neutralize/Inhibit
Swiss prot:	P11137
Form:	1 mg/ml in DI water.
Purity:	Synthetic peptide MAP-2 (W14). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp:	Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names:	Microtubule-associated protein 2; MAP2
Additional info:	This peptide can be used with studies using BS3487 MAP-2 (W14) pAb.

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MAP-2 (W14) Peptide

Cat no: BS3487P

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