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MAPKAPK-2 (S328) Peptide

MAPKAPK-2 (S328) Peptide

Cat no: BS1808P

Supplier: Bioworld Technology, Inc.
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MAP kinase activated protein kinase 2 (MAPKAP Kinase 2), also known as p45 hsp27 kinase, is a 45-54 kDa serine/threonine protein kinase that contains a proline rich sequence and two putative SH3 binding sites. MAPKAP Kinase 2 is activated in response to stress, IL1 and TNF, possibly catalyzed by p38/Hog dependent phosphorylation. One of the major substrates of MAPKAP Kinase 2 is hsp27, which stimulates actin polymerization in order to facilitate recovery from destruction of cytoskeleton during cellular stresses. MAPKAP2 is implicated in several disorders including ischemic brain injury and heart failure and has been shown to be important in regulating stress resistance and the production of TNF alpha.
Catalogue number: BS1808P
Applications: Block/Neutralize/Inhibit
Swiss prot: P49137
Form: 1 mg/ml in DI water.
Purity: Synthetic peptide MAPKAPK-2 (S328). (Note: the amino acid sequence is proprietary). The purity is > 98%.
Storage temp: Store at 4 degree C short term. Aliquot and store at -20 degree C long term. Avoid freeze-thaw cycles.
Alternative names: MAPKAP Kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAPK-2; MK2; EC 2.7.11.1; MAPKAPK2
Additional info: This peptide can be used with studies using BS1808 MAPKAPK-2 (S328) pAb.

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