MATra-si Reagent for efficient transfection of siRNA/miRNA as well as Antisense Oligos (ODN) using IBA's Magnet Assisted Transfection technology (MATra). MATra is a very gentle, easy-to-handle, fast and highly efficient technology to transfect cells in culture. Applications range from Neurosciences via Oncology to Hepatology and many more. Suitable for a large variety of cell lines and primary cells. Using this new technique, nucleic acids are in a first step associated with specific magnetic nanoparticles (MagTag(R)). Exploiting magnetic force the full nucleic acid dose is then drawn towards and delivered into the target cells leading to efficient transfection without disturbing the membrane architecture, without causing chromosomal damage or leaving a hole in the cell membrane like other transfection technologies. A special magnet plate is required, which is also available at IBA GmbH. Suitable for adherent and suspension cells (the latter in combination with MATra-S Immobilizer). Can be adapted to high-throughput transfection assays.
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